Pigmentation Disease, also known as pigmentation disorders, is related to reticulate acropigmentation of kitamura and neonatal jaundice, and has symptoms including exanthema, pruritus and polydipsia. An important gene associated with Pigmentation Disease is TYR (Tyrosinase), and among its related pathways/superpathways are Metabolism and Metapathway biotransformation Phase I and II. The drugs Aldesleukin and Tacrolimus have been mentioned in the context of this disorder. Affiliated tissues include skin and eye, and related phenotypes are growth/size/body region and renal/urinary system