Pachyonychia Congenita 2 (PC2)

Pachyonychia Congenita 2, also known as pachyonychia congenita, type 2, is related to keratosis and epidermolysis bullosa, and has symptoms including hoarseness An important gene associated with Pachyonychia Congenita 2 is KRT17 (Keratin 17), and among its related pathways/superpathways are Nervous system development and COPI-independent Golgi-to-ER retrograde traffic. Affiliated tissues include skin, and related phenotypes are nail dystrophy and epidermoid cyst