Overnutrition is related to body mass index quantitative trait locus 11 and leptin deficiency or dysfunction. An important gene associated with Overnutrition is LEP (Leptin), and among its related pathways/superpathways are Glucose / Energy Metabolism and Adipogenesis. The drugs Guanfacine and Neurotransmitter Agents have been mentioned in the context of this disorder. Affiliated tissues include breast and liver, and related phenotype is liver/biliary system.