Otosclerosis

Otosclerosis, also known as otospongiosis, is related to ankylosis and brittle bone disorder, and has symptoms including earache An important gene associated with Otosclerosis is OTSC2 (Otosclerosis 2), and among its related pathways/superpathways are Phospholipase-C Pathway and Extracellular matrix organization. The drugs Acetylcysteine and Protective Agents have been mentioned in the context of this disorder. Affiliated tissues include bone and adrenal cortex, and related phenotypes are conductive hearing impairment and otosclerosis