Osteogenesis Imperfecta, Type Xxi (OI21)

Osteogenesis Imperfecta, Type Xxi, also known as oi21, is related to osteofibrous dysplasia and fibrous dysplasia. An important gene associated with Osteogenesis Imperfecta, Type Xxi is KDELR2 (KDEL Endoplasmic Reticulum Protein Retention Receptor 2), and among its related pathways/superpathways are FGF signaling pathway and Transcription_Role of VDR in regulation of genes involved in osteoporosis. Affiliated tissues include bone, and related phenotypes are osteoporosis and joint hypermobility