Osteonecrosis of the Jaw is related to osteonecrosis and gnathodiaphyseal dysplasia. An important gene associated with Osteonecrosis of the Jaw is CYP2C8 (Cytochrome P450 Family 2 Subfamily C Member 8), and among its related pathways/superpathways are FOXO-mediated transcription and Notch Signaling Pathways. The drugs Clavulanic acid and Clindamycin have been mentioned in the context of this disorder. Affiliated tissues include bone and bone marrow, and related phenotype is neoplasm.