Orthostatic Hypotension, also known as postural hypotension, is related to pure autonomic failure and multiple system atrophy 1. An important gene associated with Orthostatic Hypotension is DBH (Dopamine Beta-Hydroxylase), and among its related pathways/superpathways are Metabolism and p70S6K Signaling. The drugs Dopamine and Fludrocortisone have been mentioned in the context of this disorder. Affiliated tissues include heart and spinal cord, and related phenotypes are homeostasis/metabolism and nervous system