Orthostatic Intolerance (OI)

Alias:

Mitral Valve Prolapse

Neurocirculatory Asthenia

Mitral Valve Prolapse Syndrome

Systolic Click-Murmur Syndrome

Irritable Heart

Cardiovascular Malfunction Arising from Mental Factors

Mitral Valve Prolapse, Familial, X-Linked

Prolapsing Mitral Valve Leaflet Syndrome

Ballooning Posterior Leaflet Syndrome

Mitral Valve Prolapse-Click Syndrome

Posterior Mitral Leaflet Deformity

Myxomatous Mitral Valve Prolapse

Billowing Mitral Valve Leaflet

Floppy Mitral Valve Syndrome

Intolerance, Orthostatic

Mitral Valvular Prolapse

Cardiovascular Neurosis

Mitral Leaflet Syndrome

Ballooning Mitral Valve

Myxomatous Mitral Valve

Systolic Click Syndrome

Flail Mitral Leaflet

Floppy Mitral Valve

Da Costa's Syndrome

Krishaber's Disease

Blue Valve Syndrome

Barlow's Syndrome

Barlow Syndrome

Soldiers Heart

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Orthostatic Intolerance, also known as mitral valve prolapse, is related to mitral valve prolapse 1 and postural orthostatic tachycardia syndrome, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Orthostatic Intolerance is SLC6A2 (Solute Carrier Family 6 Member 2), and among its related pathways/superpathways are ACE Inhibitor Pathway, Pharmacodynamics and Amino acid metabolism. The drugs Carbidopa and Prednisolone have been mentioned in the context of this disorder. Affiliated tissues include heart and spinal cord, and related phenotypes are orthostatic tachycardia and elevated urinary norepinephrine level

Related ID：

MALACARDS：ORT004

OMIM：604715

MESH：D008945

ICD11：1085590500