Ornithine Transcarbamylase Deficiency, Hyperammonemia Due to (OTCD)

Ornithine Transcarbamylase Deficiency, Hyperammonemia Due to, also known as ornithine carbamoyltransferase deficiency, is related to brain edema and reye syndrome, and has symptoms including lethargy, seizures and vomiting. An important gene associated with Ornithine Transcarbamylase Deficiency, Hyperammonemia Due to is OTC (Ornithine Transcarbamylase), and among its related pathways/superpathways are Metabolism and Regulation of expression of SLITs and ROBOs. The drugs Prednisolone and Prednisolone acetate have been mentioned in the context of this disorder. Affiliated tissues include Liver and brain, and related phenotypes are splenomegaly and aminoaciduria