Oral Hairy Leukoplakia, also known as hairy leukoplakia, is related to acquired immunodeficiency syndrome and secondary syphilis. An important gene associated with Oral Hairy Leukoplakia is KRT14 (Keratin 14). The drugs Acyclovir and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include tongue and bone marrow, and related phenotypes are immune system and hematopoietic system