Oral Submucous Fibrosis (OSMF)

Oral Submucous Fibrosis, also known as oral submucosal fibrosis, including of tongue, is related to oral cancer and deficiency anemia, and has symptoms including oral manifestations An important gene associated with Oral Submucous Fibrosis is LOX (Lysyl Oxidase), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Pentoxifylline and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include tongue and smooth muscle, and related phenotypes are narrow mouth and cheilitis