Orofacial Clefting Syndrome, also known as orofacial clefting, is related to cleft palate, isolated and orofacial cleft. An important gene associated with Orofacial Clefting Syndrome is LRP6 (LDL Receptor Related Protein 6), and among its related pathways/superpathways is Development of ureteric collection system. Affiliated tissues include b lymphoblasts and skin, and related phenotypes are Increased shRNA abundance (Z-score > 2) and nervous system