Orofacial Cleft

Orofacial Cleft(来自ICD-11)
别称:
Cleft, Orofacial
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Basic Information
Medical Symptom
Gene & Mutation
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References Literature
Orofacial Cleft, also known as cleft, orofacial, is related to cleft lip/palate-ectodermal dysplasia syndrome and orofacial cleft 4. An important gene associated with Orofacial Cleft is LRP6 (LDL Receptor Related Protein 6), and among its related pathways/superpathways are Wnt / Hedgehog / Notch and Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers. The drugs Difluocortolone and Folic acid have been mentioned in the context of this disorder. Affiliated tissues include whole blood and b lymphoblasts, and related phenotypes are limbs/digits/tail and digestive/alimentary
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MALACARDS
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靶点药物

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临床阶段
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