Optic Atrophy 11 (OPA11)

Optic Atrophy 11, also known as opa11, is related to charcot-marie-tooth disease type 2a2b and spastic ataxia 5. An important gene associated with Optic Atrophy 11 is YME1L1 (YME1 Like 1 ATPase), and among its related pathways/superpathways are Glucose / Energy Metabolism and Transcriptional activation of mitochondrial biogenesis. Affiliated tissues include brain and retina, and related phenotypes are intellectual disability and global developmental delay