Optic Nerve Neoplasm, also known as tumor of second cranial nerve, is related to epithelioid neurofibroma and neurilemmoma of the fifth cranial nerve. An important gene associated with Optic Nerve Neoplasm is NF1 (Neurofibromin 1), and among its related pathways/superpathways are Signal Transduction and RAF/MAP kinase cascade. The drug Midazolam has been mentioned in the context of this disorder. Related phenotypes are Decreased viability and Increased cell migration