Oppositional Defiant Disorder

Oppositional Defiant Disorder, also known as behavioural disorder; oppositional defiance, is related to intermittent explosive disorder and conduct disorder, and has symptoms including sleep disturbances, photophobia and personality changes. An important gene associated with Oppositional Defiant Disorder is SLC6A3 (Solute Carrier Family 6 Member 3), and among its related pathways/superpathways are GPCR downstream signalling and Class A/1 (Rhodopsin-like receptors). The drugs Aripiprazole and Guanfacine have been mentioned in the context of this disorder. Affiliated tissues include brain and amygdala, and related phenotypes are shRNA abundance <= 50% and nervous system