Oncocytoma, also known as oxyphilic adenoma, is related to renal oncocytoma and birt-hogg-dube syndrome 1. An important gene associated with Oncocytoma is MT-ND6 (Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 6), and among its related pathways/superpathways are Keratinization and COPI-independent Golgi-to-ER retrograde traffic. The drugs Trametinib and Dabrafenib have been mentioned in the context of this disorder. Affiliated tissues include salivary gland and thyroid, and related phenotypes are renal oncocytoma and Reduced mammosphere formation