Oligodendroglioma

Oligodendroglioma(来自ICD-11)

别称:

Oligodendroglial Neoplasm

Oligodendroglial Tumor

Well Differentiated Oligodendroglioma

Oligodendroglial Tumors

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Oligodendroglioma, also known as oligodendroglial neoplasm, is related to idh-mutant and 1p/19q-codeleted oligodendroglioma and oligoastrocytoma. An important gene associated with Oligodendroglioma is IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2), and among its related pathways/superpathways are Prolactin Signaling and Cellular Senescence. The drugs Trametinib and Dabrafenib have been mentioned in the context of this disorder. Affiliated tissues include brain and eye, and related phenotypes are Decreased viability and Synthetic lethal with MLN4924 (a NAE inhibitor)

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