Oculoectodermal Syndrome (OES)

Oculoectodermal Syndrome, also known as toriello-lacassie-droste syndrome, is related to encephalocraniocutaneous lipomatosis and lipomatosis. An important gene associated with Oculoectodermal Syndrome is KRAS (KRAS Proto-Oncogene, GTPase), and among its related pathways/superpathways are Nervous system development and Activation of cAMP-Dependent PKA. Affiliated tissues include skin and pineal, and related phenotypes are agenesis of corpus callosum and aplasia/hypoplasia of the skin