Obesity Due to Pro-Opiomelanocortin Deficiency, also known as pomc deficiency, is related to obesity, early-onset, with adrenal insufficiency and red hair and body mass index quantitative trait locus 11. An important gene associated with Obesity Due to Pro-Opiomelanocortin Deficiency is POMC (Proopiomelanocortin). The drugs Intermedine and Pharmaceutical Solutions have been mentioned in the context of this disorder. Affiliated tissues include skin and pituitary, and related phenotypes are obesity and increased adipose tissue