Nutritional Deficiency Disease, also known as malnutrition, is related to hypoascorbemia and pyridoxine deficiency anemia, and has symptoms including abdominal pain, cachexia and constipation. An important gene associated with Nutritional Deficiency Disease is TTR (Transthyretin), and among its related pathways/superpathways are Metabolism of proteins and Glucose / Energy Metabolism. The drugs Parecoxib and Parathyroid hormone have been mentioned in the context of this disorder. Affiliated tissues include heart and liver, and related phenotypes are Reduced mammosphere formation and homeostasis/metabolism