Neurotic Excoriation, also known as factitious skin disease, is related to pemphigus and pemphigoid, and has symptoms including pruritus, pruritus ani and genital itching. An important gene associated with Neurotic Excoriation is COL7A1 (Collagen Type VII Alpha 1 Chain), and among its related pathways/superpathways are Collagen chain trimerization and Extracellular matrix organization. The drugs Acetylcysteine and Lamotrigine have been mentioned in the context of this disorder. Affiliated tissues include skin and breast.