Norrie Disease (ND)

Norrie Disease, also known as atrophia bulborum hereditaria, is related to persistent hyperplastic primary vitreous, autosomal recessive and exudative vitreoretinopathy 2, x-linked. An important gene associated with Norrie Disease is NDP (Norrin Cystine Knot Growth Factor NDP), and among its related pathways/superpathways are Signaling by WNT and ncRNAs involved in Wnt signaling in hepatocellular carcinoma. The drugs Sodium citrate and Lithium carbonate have been mentioned in the context of this disorder. Affiliated tissues include eye and retina, and related phenotypes are cataract and corneal opacity