Neuropathy, Ataxia, and Retinitis Pigmentosa (NARP)

Neuropathy, Ataxia, and Retinitis Pigmentosa, also known as narp syndrome, is related to isolated atp synthase deficiency and hereditary optic neuropathy, and has symptoms including ataxia, seizures and proximal neurogenic muscle weakness. An important gene associated with Neuropathy, Ataxia, and Retinitis Pigmentosa is MT-ATP6 (Mitochondrially Encoded ATP Synthase Membrane Subunit 6), and among its related pathways/superpathways are Metabolism and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. Affiliated tissues include eye and retina, and related phenotypes are seizure and nystagmus