Neuronal Migration Disorders

Neuronal Migration Disorders, also known as abnormality of neuronal migration, is related to lissencephaly 1 and hemimegalencephaly. An important gene associated with Neuronal Migration Disorders is ASNS (Asparagine Synthetase (Glutamine-Hydrolyzing)), and among its related pathways/superpathways are Lissencephaly gene (LIS1) in neuronal migration and development and PAFAH1B1 copy number variation. Affiliated tissues include brain and cerebellum, and related phenotype is Increased shRNA abundance (Z-score > 2).