Neural Tube Defects, Folate-Sensitive (NTDFS)

Neural Tube Defects, Folate-Sensitive, also known as neural tube defect, folate-sensitive, is related to neural tube defects and vitamin b12 deficiency. An important gene associated with Neural Tube Defects, Folate-Sensitive is MTHFR (Methylenetetrahydrofolate Reductase), and among its related pathways/superpathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. The drugs Drospirenone and diuretics have been mentioned in the context of this disorder. Affiliated tissues include heart and spinal cord, and related phenotypes are abnormality of metabolism/homeostasis and spinal dysraphism