Near-Fatal Asthma is related to ige responsiveness, atopic and respiratory failure. An important gene associated with Near-Fatal Asthma is IL5 (Interleukin 5), and among its related pathways/superpathways are MIF Mediated Glucocorticoid Regulation and Cytokine Signaling in Immune system. Affiliated tissues include smooth muscle and t cells, and related phenotypes are immune system and digestive/alimentary