Neurodegeneration with Brain Iron Accumulation 4 (NBIA4)

Neurodegeneration with Brain Iron Accumulation 4, also known as nbia4, is related to spastic paraplegia 43, autosomal recessive and iron metabolism disease, and has symptoms including ataxia, muscle spasticity and tremor. An important gene associated with Neurodegeneration with Brain Iron Accumulation 4 is C19orf12 (Chromosome 19 Open Reading Frame 12), and among its related pathways/superpathways are Autophagy and Iron metabolism disorders. The drug Iron has been mentioned in the context of this disorder. Affiliated tissues include brain and globus pallidus, and related phenotypes are global developmental delay and cerebellar atrophy