Neurodegeneration with Brain Iron Accumulation 3 (NBIA3)

Neurodegeneration with Brain Iron Accumulation 3, also known as neuroferritinopathy, is related to movement disease and parkinsonism, and has symptoms including cerebellar ataxia, muscle rigidity and tremor. An important gene associated with Neurodegeneration with Brain Iron Accumulation 3 is FTL (Ferritin Light Chain), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Glucose / Energy Metabolism. The drug Iron has been mentioned in the context of this disorder. Affiliated tissues include brain and cerebellum, and related phenotypes are cognitive impairment and dystonia