Narcolepsy 2 (NRCLP2)

Alias:
Narcolepsy 2, Susceptibility to
Narcolepsy Without Cataplexy
Narcolepsy Without Cataplexy and Hypocretin Deficiency
Narcolepsy Type 2
Nrclp2
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Narcolepsy 2, also known as narcolepsy without cataplexy, is related to idiopathic hypersomnia and hypersomnia. An important gene associated with Narcolepsy 2 is NRCLP2 (Narcolepsy, HLA-Associated), and among its related pathways/superpathways are CD28 Signaling in T-Helper Cell and Immune response Function of MEF2 in T lymphocytes. The drugs Dopamine and Mazindol have been mentioned in the context of this disorder. Affiliated tissues include eye and temporal lobe, and related phenotypes are hallucinations and insomnia
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Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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Child
1-5/10000
4
40
1

Medical Symptom

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Description
HPO Frequency
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HPO Source Accession
No data available

Gene & Mutation

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No data available

Disease Model

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Name
MGI
Related Gene
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Publications
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References Literature

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