Nephronophthisis 2 (NPHP2)

Nephronophthisis 2, also known as nphp2, is related to infantile nephronophthisis and end stage renal disease. An important gene associated with Nephronophthisis 2 is INVS (Inversin), and among its related pathways/superpathways are Loss of Nlp from mitotic centrosomes and Organelle biogenesis and maintenance. Affiliated tissues include kidney and lung, and related phenotypes are stage 5 chronic kidney disease and renal cortical microcysts