Nephrosclerosis

Nephrosclerosis, also known as renal sclerosis, is related to malignant hypertension and renal artery atheroma. An important gene associated with Nephrosclerosis is ACE (Angiotensin I Converting Enzyme), and among its related pathways/superpathways are Signal Transduction and p70S6K Signaling. The drugs Angiotensin II and Valsartan have been mentioned in the context of this disorder. Affiliated tissues include kidney and endothelial, and related phenotypes are Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) and homeostasis/metabolism