Nontoxic Goiter

Alias:

Retrosternal Thyroid Struma

Thyroid Gland Hypertrophy

Thyroid Gland Hyperplasia

Swelling of Thyroid Gland

Nodule-Thyroid, Non Tox

Non-Toxic Simple Goitre

Substernal Thyroid Mass

Sporadic Nodular Struma

Nontoxic Nodular Goitre

Enlarged Thyroid Gland

Hypertrophic Thyroid

Intrathoracic Goitre

Thyroid Hypertrophy

Thyroid Hyperplasia

Retrosternal Goitre

Hyperplastic Goitre

Substernal Thyroid

Goiter, Non-Toxic

Goitre, Non-Toxic

Substernal Goitre

Struma of Thyroid

Non-Toxic Goitre

Plunging Goitre

Nodular Goitre

Nodular Struma

Form of Goitre

Goitre Struma

Thyromegaly

Goitre Nos

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Nontoxic Goiter, also known as retrosternal thyroid struma, is related to goiter, multinodular 1, with or without sertoli-leydig cell tumors and hypothyroidism, congenital, nongoitrous, 2. An important gene associated with Nontoxic Goiter is TG (Thyroglobulin), and among its related pathways/superpathways are Transcription_Role of VDR in regulation of genes involved in osteoporosis and Development_Hedgehog and PTH signaling pathways in bone and cartilage development. The drugs Methimazole and Hormone Antagonists have been mentioned in the context of this disorder. Affiliated tissues include thyroid and pituitary, and related phenotypes are Increased shRNA abundance (Z-score > 2) and endocrine/exocrine gland

Related ID：

MALACARDS：NNT010

ICD11：854564573