Nonsyndromic Paraganglioma

Nonsyndromic Paraganglioma, also known as extra-adrenal paraganglioma, is related to paraganglioma and carotid body cancer. An important gene associated with Nonsyndromic Paraganglioma is SDHB (Succinate Dehydrogenase Complex Iron Sulfur Subunit B). The drugs Temsirolimus and Sirolimus have been mentioned in the context of this disorder. Affiliated tissues include kidney and spinal cord, and related phenotypes are Increased shRNA abundance (Z-score > 2) and renal/urinary system