Non-Secretory Myeloma is related to heavy chain disease and amyloidosis. An important gene associated with Non-Secretory Myeloma is MYOM2 (Myomesin 2), and among its related pathways/superpathways are NF-kappaB Signaling and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. Affiliated tissues include bone marrow and bone.