Nondisjunction

Alias:

Mosaicism, Chromosomal

Mixoploidy, Familial

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Nondisjunction, also known as mosaicism, chromosomal, is related to down syndrome and trisomy x. An important gene associated with Nondisjunction is MTHFR (Methylenetetrahydrofolate Reductase), and among its related pathways/superpathways are Methotrexate Pathway (Cancer Cell), Pharmacodynamics and Pharmacokinetics and MTHFR deficiency. Affiliated tissues include bone marrow and testes, and related phenotypes are decreased fertility and abnormality of chromosome segregation

Related ID：

MALACARDS：NND010

OMIM：158250