Nail Disease, also known as abnormality of the nail, is related to tinea unguium and psoriasis 11, and has symptoms including exanthema, pruritus and clubbing of nail. An important gene associated with Nail Disease is FZD6 (Frizzled Class Receptor 6), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Tazarotene and Polihexanide have been mentioned in the context of this disorder. Affiliated tissues include skin and lung, and related phenotypes are Reduced mammosphere formation and homeostasis/metabolism