Nakajo Syndrome

Nakajo Syndrome is related to proteasome-associated autoinflammatory syndrome 1 and proteasome-associated autoinflammatory syndrome, and has symptoms including arthralgia, muscle weakness and bone pain. An important gene associated with Nakajo Syndrome is PSMB8 (Proteasome 20S Subunit Beta 8), and among its related pathways/superpathways are PIP3 activates AKT signaling and Regulation of expression of SLITs and ROBOs. Affiliated tissues include skin and bone.