Necrobiosis Lipoidica

Necrobiosis Lipoidica, also known as oppenheim-urbach disease, is related to skin atrophy and systemic scleroderma. An important gene associated with Necrobiosis Lipoidica is INS (Insulin), and among its related pathways/superpathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Hematopoietic Stem Cells and Lineage-specific Markers. Affiliated tissues include skin and neutrophil, and related phenotypes are inflammatory abnormality of the skin and annular cutaneous lesion