Myxedema

Myxedema is related to autoimmune polyendocrine syndrome, type ii and toxic diffuse goiter. An important gene associated with Myxedema is TSHR (Thyroid Stimulating Hormone Receptor), and among its related pathways/superpathways are G alpha (s) signalling events and Thyroid hormones production and peripheral downstream signaling effects. Affiliated tissues include thyroid and skin, and related phenotypes are growth/size/body region and endocrine/exocrine gland