Myopathy with Extrapyramidal Signs (MPXPS)

Myopathy with Extrapyramidal Signs, also known as proximal myopathy with extrapyramidal signs, is related to muscular dystrophy, limb-girdle, autosomal recessive 1 and dysferlinopathy, and has symptoms including tremor and involuntary movements. An important gene associated with Myopathy with Extrapyramidal Signs is MICU1 (Mitochondrial Calcium Uptake 1), and among its related pathways/superpathways are DREAM Repression and Dynorphin Expression and Mitochondrial calcium ion transport. Affiliated tissues include eye and brain, and related phenotypes are chorea and global developmental delay