Myeloproliferative Disorder, Chronic, with Eosinophilia (MPE)

Alias:
Myeloproliferative Disorder with Eosinophilia
Mpe
Chronic Myeloproliferative Disorder with Eosinophilia
Myeloproliferative Disorder Chronic with Eosinophilia
Chronic Myeloproliferative Disease, Unclassifiable
Undifferentiated Myeloproliferative Disease
Myeloproliferative Neoplasm, Unclassifiable
Eosinophils, Malignant Proliferation of
Malignant Proliferation of Eosinophils
Malignant Eosinophil Proliferation
Cmpd-U
Emp
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Myeloproliferative Disorder, Chronic, with Eosinophilia, also known as myeloproliferative disorder with eosinophilia, is related to hypereosinophilic syndrome and myeloproliferative neoplasm. An important gene associated with Myeloproliferative Disorder, Chronic, with Eosinophilia is PDGFRB (Platelet Derived Growth Factor Receptor Beta), and among its related pathways/superpathways are Infectious disease and PI3K-Akt signaling pathway. The drugs Fludarabine and Tacrolimus have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and myeloid, and related phenotypes are eosinophilia and myeloproliferative disorder

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
Unknown
1-9/1000000
6
66
5

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

#
Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
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