Myeloid and Lymphoid Neoplasms with Eosinophilia and Abnormalities of Pdgfra, Pdgfrb, and Fgfr1

Myeloid and Lymphoid Neoplasms with Eosinophilia and Abnormalities of Pdgfra, Pdgfrb, and Fgfr1, also known as myeloid and lymphoid neoplasms with eosinophilia and abnormalities of platelet-derived growth factor receptor alpha , platelet-derived growth factor receptor beta , and fibroblast growth factor receptor-1 are a group of hematologic neoplasms, is related to myeloid and lymphoid neoplasms associated with pdgfra rearrangement and myeloid and lymphoid neoplasms associated with fgfr1 abnormalities. An important gene associated with Myeloid and Lymphoid Neoplasms with Eosinophilia and Abnormalities of Pdgfra, Pdgfrb, and Fgfr1 is CHP1 (Calcineurin Like EF-Hand Protein 1), and among its related pathways/superpathways are RAF/MAP kinase cascade and Hippo-Merlin signaling dysregulation. Affiliated tissues include myeloid, and related phenotype is Increased colony dispersion (increased number of colonies and decreased number of cells per colony).