Myelopathy, Htlv-1-Associated, also known as familial spastic paraparesis, htlv-1-associated, is related to tropical spastic paraparesis and t-cell acute lymphoblastic leukemia. An important gene associated with Myelopathy, Htlv-1-Associated is CNTN2 (Contactin 2). The drugs Pentoxifylline and Vasodilator Agents have been mentioned in the context of this disorder. Affiliated tissues include t cells, and related phenotypes are abnormal pyramidal sign and spastic paraparesis