Myelofibrosis (MYELOF)

Alias:

Primary Myelofibrosis

Myelofibrosis with Myeloid Metaplasia

Agnogenic Myeloid Metaplasia

Idiopathic Myelofibrosis

Osteomyelofibrosis

Myeloid Metaplasia

Chronic Idiopathic Myelofibrosis

Megakaryocytic Myelosclerosis

Myelofibrosis, Idiopathic

Myelosclerosis

Agnogenic Myeloid Metaplasia with Myelofibrosis

Myelofibrosis, with Myeloid Metaplasia, Somatic

Myelofibrosis with Myeloid Metaplasia, Somatic

Myelosclerosis with Myeloid Metaplasia

Myelofibrosis, Somatic

Bone Marrow Fibrosis

Aleukemic Myelosis

Myelofibrosis Nos

Myelof

Ammm

Mmm

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Myelofibrosis, also known as primary myelofibrosis, is related to myeloproliferative neoplasm and thrombocytosis. An important gene associated with Myelofibrosis is MPL (MPL Proto-Oncogene, Thrombopoietin Receptor), and among its related pathways/superpathways are TGF-Beta Pathway and PAK Pathway. The drugs Lactitol and Lenograstim have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and myeloid, and related phenotypes are abnormal bone marrow cell morphology and splenomegaly

Related ID：

MALACARDS：MYL005

OMIM：254450

MESH：D009191

ICD11：336704235