Myeloid Sarcoma

Alias:
Granulocytic Sarcoma
Chloroma
Extramedullary Myeloid Tumor
Myeloid Sarcoma Without Mention of Remission
Myeloid Sarcoma Disease
Sarcoma, Granulocytic
Sarcoma Granulocytic
Myeloid Sarcoma Nos
Sarcoma, Myeloid
Myelosarcoma
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Myeloid Sarcoma, also known as granulocytic sarcoma, is related to acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) and acute myeloid leukemia with t(8;21)(q22;q22) translocation. An important gene associated with Myeloid Sarcoma is MPO (Myeloperoxidase), and among its related pathways/superpathways are Innate Immune System and NF-kappaB Signaling. The drugs Mitoxantrone and Picropodophyllin have been mentioned in the context of this disorder. Affiliated tissues include myeloid and bone marrow, and related phenotypes are immune system and neoplasm
Related ID:
MESH:D023981
ICD11:1988933820

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
All ages
<1/1000000
20
334
--

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

#
Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
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