Mutism

Mutism is related to akinetic mutism and von economo's disease, and has symptoms including aphonia, sleep disturbances and photophobia. An important gene associated with Mutism is SHANK3 (SH3 And Multiple Ankyrin Repeat Domains 3), and among its related pathways/superpathways are Neuroscience and Involvement of -secretase in neurodegenerative diseases. The drugs Fluoxetine and Neurotransmitter Agents have been mentioned in the context of this disorder. Affiliated tissues include brain and cerebellum, and related phenotypes are Increased shRNA abundance (Z-score > 2) and nervous system