Motion Sickness, also known as airsickness, is related to space motion sickness and migraine with or without aura 1, and has symptoms including nausea, medically unexplained symptoms and hypertriglyceridemic waist. An important gene associated with Motion Sickness is HTR3B (5-Hydroxytryptamine Receptor 3B), and among its related pathways/superpathways are GPCR downstream signalling and Signal Transduction. The drugs Histamine and Promethazine have been mentioned in the context of this disorder. Affiliated tissues include skin and brain, and related phenotypes are abnormality of the nervous system and behavior/neurological