Metagonimiasis, also known as trematode infections, is related to fascioliasis and clonorchiasis. An important gene associated with Metagonimiasis is MT-CO1 (Mitochondrially Encoded Cytochrome C Oxidase I), and among its related pathways/superpathways are Immune response IL-2 activation and signaling pathway and Immune response Antigen presentation by MHC class II. The drugs Entecavir and Lactulose have been mentioned in the context of this disorder. Affiliated tissues include heart and brain, and related phenotypes are growth/size/body region and integument