Mitochondrial Complex I Deficiency, Nuclear Type 16 (MC1DN16)

Mitochondrial Complex I Deficiency, Nuclear Type 16, also known as mc1dn16, is related to wet beriberi and beriberi. An important gene associated with Mitochondrial Complex I Deficiency, Nuclear Type 16 is NDUFAF5 (NADH:Ubiquinone Oxidoreductase Complex Assembly Factor 5), and among its related pathways/superpathways are Metabolism and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. Affiliated tissues include liver and brain, and related phenotypes are seizure and spasticity